Intersection cross-cut: sensor-microfluidic-sweat-collection ∩ algo-hydration-status

Axes: sensors × algorithms

3 corpus entries disclose both tags.

Earliest disclosure: 1965-08-01

These entries are the direct inputs to OBVIOUSNESS_TEMPLATE.md. Any patent claim combining these two elements is anticipated or rendered obvious by the chain below.

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Dune ‘stillsuit’ (body-moisture reclamation garment) (1965-08-01)

• id: dune-stillsuit
• corpus: fictional
• form factor: garment
• creator: Frank Herbert
• disclosure: Herbert, Frank. Dune. Chilton Books, 1965 — a full-body garment with layered reclamation membranes that capture perspiration, respiration moisture, and other body fluids, filter and recycle the water, and monitor fit and function so the wearer can survive desert exposure.
• ip status: fictional
• sensors: sensor-microfluidic-sweat-collection, sensor-sweat-rate
• algorithms: algo-hydration-status
• prior art notes: Discloses a body-conforming garment with integrated microfluidic channels that collect and process perspiration (and other body fluids) from the skin surface, with monitoring of collection rate, fit, and the wearer’s hydration state. Directly relevant to sweat-collecting / sweat-analysis wearable claims combining ‘a skin-contacting garment or patch’, ‘microfluidic channels to collect perspiration’, and ‘a determination of hydration or fluid balance’. § 103 motivation that the sweat-collecting body garment with hydration monitoring was an articulated objective by 1965 — decades before the epidermal-microfluidics patent wave. Non-enabling on the membrane chemistry; pair with enabling microfluidic-sweat-sensor art.

Gao et al. (Javey group) (2016) — fully integrated wearable sensor array for multiplexed in-situ perspiration analysis (2016-01-28)

• id: gao-javey-2016-wearable-sweat-sensor-array
• corpus: academic
• form factor: headband
• creator: Wei Gao et al. / Ali Javey group (UC Berkeley)
• disclosure: Gao W, Emaminejad S, Nyein HYY, Challa S, Chen K, Peck A, et al. (Javey A). ‘Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis.’ Nature 2016;529(7587):509-514.
• ip status: public-domain
• sensors: sensor-lactate, sensor-glucose-cgm, sensor-electrolyte, sensor-ph, sensor-skin-temperature, sensor-microfluidic-sweat-collection
• algorithms: algo-electrolyte-trend, algo-hydration-status
• prior art notes: Discloses a fully integrated wearable (wristband / headband) with an array of electrochemical sensors measuring multiple sweat analytes simultaneously (glucose, lactate, Na+, K+) plus skin temperature for real-time signal compensation, with on-board signal conditioning, microcontroller, and wireless transmission to a phone — i.e. a complete in-situ sweat biochemistry monitor. Any wearable claim reciting ‘a band-form device with an array of two or more electrochemical sweat-analyte sensors plus a temperature sensor for compensation, with integrated electronics and wireless output’ reads on Gao/Javey 2016. Anchor for the sweat-electrochemical-sensing cross-cuts on the real side; [[bandodkar-wang-2014-wearable-electrochemical-sensors-review]] is the contemporaneous review.

Koh et al. (Rogers group) (2016) — soft wearable microfluidic device for sweat capture, storage, and colorimetric sensing (2016-11-23)

• id: koh-rogers-2016-soft-microfluidic-sweat-device
• corpus: academic
• form factor: patch
• creator: Ahyeon Koh et al. / John A. Rogers group (Northwestern)
• disclosure: Koh A, Kang D, Xue Y, Lee S, Pielak RM, Kim J, et al. (Rogers JA). ‘A soft, wearable microfluidic device for the capture, storage, and colorimetric sensing of sweat.’ Science Translational Medicine 2016;8(366):366ra165.
• ip status: public-domain
• sensors: sensor-microfluidic-sweat-collection, sensor-sweat-rate, sensor-ph, sensor-lactate, sensor-electrolyte, sensor-glucose-cgm
• algorithms: algo-hydration-status, algo-electrolyte-trend
• prior art notes: Discloses a soft, skin-mounted microfluidic ‘sticker’ that wicks sweat from the skin into a network of microchannels and reservoirs, measures sweat rate and total sweat loss, and performs colorimetric assays (pH, chloride, lactate, glucose) read out by eye or smartphone camera. Any wearable claim reciting ‘a skin-mounted patch with microfluidic channels collecting perspiration’ combined with ‘rate measurement’ and/or ‘colorimetric or electrochemical analysis of constituents’ reads on Koh/Rogers 2016. Anchor for the patch × microfluidic-sweat-collection cross-cut on the real side; [[dune-stillsuit]] (1965) is the fictional antecedent.