Cross-cut: `sensor-bioimpedance`

Axis: sensors

2 corpus entries disclose this tag.

Earliest disclosure: 2017-11-14

Listed in chronological order. Each entry’s prior_art_notes and disclosure_citation constitute the citeable prior art material.

Abilify MyCite (Otsuka / Proteus Digital Health, 2017) — first FDA-approved drug with an ingestible sensor (digital-pill / medication-adherence system) (2017-11-14)

id: proteus-abilify-mycite-2017
corpus: private
form factor: ingestible
creator: Otsuka Pharmaceutical Co. / Proteus Digital Health, Inc.
disclosure: Otsuka Pharmaceutical Co., Ltd. and Proteus Digital Health, Inc. ‘Abilify MyCite’ (aripiprazole with embedded ingestible event marker), FDA-approved 13 November 2017 — the first drug-device combination approved by the FDA with an integrated ingestible sensor: a millimeter-scale sensor embedded in each tablet that activates on contact with stomach fluid and transmits to a skin-worn patch (‘MyCite Patch’), which relays an ingestion event to a smartphone, confirming medication adherence.
ip status: patented
sensors: sensor-bioimpedance
prior art notes: Discloses a drug-device combination in which each medication tablet incorporates a tiny edible sensor that activates on contact with stomach fluid (powered by the electrochemical reaction with stomach acid), communicating an ingestion event to a skin-mounted receiver patch that relays it to a smartphone. The first FDA-approved digital-pill / medication-adherence-tracking system. Anticipates ingestible-sensor medication-adherence claims combining ‘an ingestible sensor embedded in or co-delivered with a pharmaceutical’, ‘a skin-worn receiver/patch’, and ‘transmission of an ingestion-event record’ from 2017. Anchor for the ingestible × adherence cross-cut.

id: heikenfeld-2018-wearable-sensors-lab-on-chip-review
corpus: academic
form factor: other
creator: Jason Heikenfeld et al.
disclosure: Heikenfeld J, Jajack A, Rogers J, Gutruf P, Tian L, Pan T, Li R, Khine M, Kim J, Wang J, Kim J. ‘Wearable sensors: modalities, challenges, and prospects.’ Lab on a Chip 2018;18(2):217-248.
ip status: public-domain
sensors: sensor-ppg, sensor-ecg, sensor-eeg, sensor-glucose-cgm, sensor-lactate, sensor-cortisol, sensor-skin-temperature, sensor-bioimpedance
prior art notes: Authoritative 2018 review collecting wearable sensing across modalities — physical (motion, BCG/SCG, mechanoacoustic), electrophysiological (ECG/EMG/EEG), optical (PPG/SpO2, near-IR), thermal, electrochemical (sweat, saliva, tears, interstitial), and stimulation-coupled — across form factors (patch, watch, tattoo, contact lens, garment) and the challenges of body-fluid sampling, calibration, motion-artifact handling, and skin-electronics interfacing. Prior art establishing that the modality/form-factor combinations enumerated here were collected and surveyed by 2018; useful against later claims to those combinations. General anchor.